Investigation of Acute Toxicity and Biological Activity of an Extract obtained on the Basis of a Local Medicinal Herbal Collection

https://doi.org/10.55529/jcpp.35.8.14

Authors

  • Akhranova Sokhiba Tazhidinovna Senior researcher of Department of Microbiology and Pharmacology of Tashkent dentistry institute, Uzbekistan.

Keywords:

Local Medicinal Plants, Acute Toxicity, Extract, Alimentary Anemia, Hemolytic Anemia.

Abstract

The presented article describes the results of research work on the alimentary and hemolytic anemic effect of herbal decoction of medicinal properties, which is used in folk medicine for the treatment of various diseases. The extract of the sum of decoctions of medicinal plants was administered orally to experimental rabbits for 60 days in an amount of 10 ml / kg and 25 ml / kg, and their antianemic activity was assessed by such indicators as the number of shaped blood elements, as well as the general condition of experimental animals and changes in weight. Extract of tincture of sum of medicinal plants in studies of therapeutic effect in alimentary anemia on the other hand, already on the 7th day of treatment, the effect against hemolytic anemia began to manifest itself in less than 21 days, and it becomes more intense until the end of the experiment. These effects were manifested by a positive change in the number of shaped blood elements, an improvement in the general condition of experimental animals, a significant increase in appetite, and the restoration of lost body weight. This entails extensive scientific studies of the activity and mechanism of action of this tincture against the background of various anemia.

Published

2023-08-18

How to Cite

Tazhidinovna, A. S. . (2023). Investigation of Acute Toxicity and Biological Activity of an Extract obtained on the Basis of a Local Medicinal Herbal Collection. Journal of Community Pharmacy Practice, 3(05), 8–14. https://doi.org/10.55529/jcpp.35.8.14

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