Journal of Prevention, Diagnosis and Management of Human Diseases (JPDMHD) 2799-1202 <p>The <strong>Journal of Prevention, Diagnosis and Management of Human Diseases (JPDMHD)</strong> <strong>having ISSN:2799-1202</strong> is a double-blind, peer-reviewed, open access journal that provides publication of articles in all areas of Human Diseases and related disciplines. The objective of this journal is to provide a veritable platform for scientists and researchers all over the world to promote, share, and discuss a variety of innovative ideas and developments in all aspects of <strong>Human Diseases and related disciplines.</strong></p> HM Journals en-US Journal of Prevention, Diagnosis and Management of Human Diseases (JPDMHD) 2799-1202 2799-1202 Evaluation of Some Biochemical Variables among Smoker Athletes in Kirkuk City <p>The study aimed to evaluate the levels of some biochemical variables such as vitamins C, E, and D, as well as albumin and uric acid levels, in addition to levels of fatty proteins in the blood serum of a group of smoking athletes and compare the results with the levels of these biochemical variables in non-smoking athletes (as a control group). The study sample included 100 individuals divided into two groups: smoking athletes (60 individuals) and non-smoking athletes (40 individuals), in addition to calculating the Body Mass Index (BMI).The study results showed lower levels of vitamins C and E in smokers athletes compared to non-smokers athletes, while vitamin D levels were low in both smokers and non-smokers athletes. The results also showed a decrease in albumin and uric acid levels in smokers’ athletes. Additionally, levels of fatty proteins (T.G, Cholesterol, HDL, LDL, VLDL) were measured, and the levels were within the normal range for both smokers and non-smokers athletes.</p> Essa Omran Jassim Sayran Sattar Saleh Copyright (c) 2024 Authors 2024-04-01 2024-04-01 4 03 1 8 10.55529/jpdmhd.43.1.8 Assessment of Some Biometrics and Biochemical Parameters in Migraine Patients <p>Background: Migraine is a pulsating and recurrent headache in one or both side. It may be caused by induce of nerves in the brain blood vessels walls and its associates with photophobia. Objectives: Measure of Body mass index (BMI), blood pressure (BP), serum calcium (Ca), magnesium (Mg) and iron (Fe) in migraine patients. Methods: This study performed on 94 persons (64 migraine: 30 control), who visited Al-Duloya General Hospital, Tikrit Educational Hospital, and neurological clinics in Al-Duloya and Tkrit. Also it contains visiting participants to their homes in Salahaddin in Iraq. A socio-demographic characters, length, weight, and BP taken directly. 3-5ml blood sampled for obtaining serum. Biochemical tests analyzed by spectrophotometer in Central laboratory of Tikrit University. The study period extended from 30-7-2023 to 27-9-2023. GraphPrism9 program and T-test used for statistical analysis. Results: Patient age was 34.9(16-63) year. Higher percentages reported in female (79.6%) and family history (68.7%). BMI (29.1±5.5), (27.6±5.3) kg/m2, systolic BP (11.7±1.2), (11.5±1.1), and diastolic BP (7.5±0.8), (7.2±1.0) Cm.Hg, show non-significant elevation in migraine compare with control respectively. Mg reveals significant decrease (1.7±0.7), (2.1±0.6), but Ca (7±0.5), (7.3±0.7) and Iron (82±57), (90±52) mg/dL reveal non-significant decrease in migraine compare with control respectively. Conclusions: BMI and BP show non-significant elevation. While Mg reveals significant decrease, Ca and Iron reveal non-significant decrease in patients.</p> Faiz Ali Al-Mfrgi Maan Hasan Salih Copyright (c) 2024 Authors 2024-04-01 2024-04-01 4 03 9 17 10.55529/jpdmhd.43.9.17 Blood Sugar Concentration, HbA1C, and Lipid Profile in Heart Patients <p>The study included 45 samples (30 patients with heart disease and have diabetes and 15 patients with Type 2 DM), their age between (40-60) years for both gender. Samples were collected from Kirkuk general hospital from April 2023 to September 2023. The individuals of this study were divided into two groups: The first group was for patients with heart disease n (30), and the second group for individual have diabetes only n (15). Result: Heart disease patients had higher mean serum cholesterol, triglyceride, LDL, and VLDL levels (225.1±25.2, 209.5±8.3, 140.7±17.9, 41.9±4.61) compared to diabetes patients (196.3±27.2, 165±6.1, 119.67±15.2, 33.00±3.22) at a P-value &lt; 0.05. HDL levels were similar across groups at P &gt; 0.05. The research demonstrates the mean FBS and HbA1C of 30 heart disease and 15 diabetic patients. The study found that heart disease patients had higher mean serum FBS and HbA1C levels (282.8±36.41 mg/dl, 10.35±3.18%) compared to diabetes patients (175.2±32.79 mg/dl, 8.22±2.51%). A P-value &lt; 0.05. Conclusion: The study concluded appositive association between dyslipidemia and heart disease in which increased cholesterol, triglyceride, low-density lipoprotein (LDL), very-low-density lipoprotein (VLDL), fasting blood glucose and HbA1C and no differences between heart disease and diabetes patients.</p> Ruaa Hussein Alwan Copyright (c) 2024 Authors 2024-04-03 2024-04-03 4 03 18 26 10.55529/jpdmhd.43.18.26 Evaluation of Some Immunological Parameters against Streptococcus Pyogenes in Tonsillitis <p>This study was designed to evaluate some immunological parameters in patients with chronic tonsillitis. Swabs were obtained from the tonsils of 120 patients with chronic tonsillitis to detect streptococcus pyogenes and. and blood samples collected to detect the immune parameters in the patient's serum. The results of culture showed that 60 samples (50%) were positive to streptococcus pyogenes. Significant differences were observed in ASO titer levels between the tonsillitis group (400 IU, interquartile range: 400-1600) and the control group (200 IU, interquartile range: 0), with a p-value &lt;0.05. However, no statistically significant differences were observed in TNF-α levels between the two groups, with a median of 248 pg/ml (interquartile range: 125) in the tonsillitis group and 209 pg/ml (interquartile range: 112) in the control group (p&gt;0.05). Nevertheless, a significant decrease in IL-10 levels was observed in the tonsillitis group (51.8 pg/ml, interquartile range: 29.4) compared to the control group (81.4 pg/ml, interquartile range: 36.4), with a p-value &lt;0.05.</p> Nebras Ayad Mohammed Sundus Jassim Muhammad Abdulwadood Shakir Mahmood Alsoufi Copyright (c) 2024 Authors 2024-04-11 2024-04-11 4 03 27 32 Quality of Life of Kidney Transplant Donor at Shahid Dharmabhakta National Transplant Centre, Nepal <p>Introduction: End-stage renal disease has a high rate of mortality and morbidity globally. Kidney transplantation remains the best treatment option in comparison to other forms of renal replacement. This study was carried out to compare QOL before and after donor nephrectomy. The aim of study was to assess the quality of life of the living donor Methods: A prospective cross-sectional study was conducted among 80 renal transplant donors of Shahid Dharmbhakta National Transplant Centre from February 2021 to February 2022. A consecutive sampling technique was done for data collection. Short Form 36 version 2 (SF36v2) was used to assess the quality of life of kidney donors. The interview was conducted by researcher just before and twelve months after the donor nephrectomy who came for follow up in that center. Score of eight domains of quality of life before and after transplant were compared with paired t-tests through SPSS software 20. Results: Out of eight domains of quality of life, physical functioning, fatigue, emotional well-being, pain and general health were decreased 12 months after donation. Domains of QOL; physical functioning, limitation due to physical health, Role limitation due to emotional problems, Energy Role, fatigue , Emotional wellbeing , social functioning, pain and general health, were compared using paired T-test. The result showed (M= 70.60 SD=18.67) before transplant and M= 66.92 SD= 17.30 one year post transplant. Mean decrease is M= 3.68, SD= 3.56, df= 7, (95% Cl 0.7, 6.6), p=0.02. Domain of Quality of life like Physical functioning (p=0.001), limitation due to physical health (p=0.01), energy role fatigue (p=0.001), pain and general health (p=0.001) were significantly associated with kidney donation in donors. Conclusion: The quality of life of renal transplant donors was affected by donor nephrectomy.</p> Archana Bagale Dr. Swostik Pradhananga Saru Koju Copyright (c) 2024 Authors 2024-04-12 2024-04-12 4 03 33 39