Evaluation of the Effect on the Nervous System of Substances with an Alkaloid Structure Having Antitumor Activity

Yu. R. Mirzaev; T. T. Khamroev; E. M. Ruzimov; B. N. Khandamov; Sh. M. Adizov

doi:10.55529/jhtd.26.6.10

Evaluation of the Effect on the Nervous System of Substances with an Alkaloid Structure Having Antitumor Activity

https://doi.org/10.55529/jhtd.26.6.10

Authors

Yu. R. Mirzaev Candidate of Medical Sciences, senior scientific Researcher at the S.Yu. Yunusov Institute of Plant Chemistry of the Academy of Sciences of the Republic of Uzbekistan
T. T. Khamroev Basic doctoral student of the Institute of Plant Chemistry named after S.Yu. Yunusov of the Academy of Sciences of the Republic of Uzbekistan
E. M. Ruzimov Junior scientific Researcher at the S.Y. Yunusov Institute of Plant Chemistry of the Academy of Sciences of the Republic of Uzbekistan
B. N. Khandamov Basic doctoral student of the Institute of Plant Chemistry named after S.Yu. Yunusov of the Academy of Sciences of the Republic of Uzbekistan
Sh. M. Adizov PhD, Senior scientific Researcher at the S.Yu. Yunusov Institute of Plant Chemistry of the Academy of Sciences of the Republic of Uzbekistan

Keywords:

Sedative, Pirazolone Iodine Methylate, Pirazoline Chloride, Sonberg Method, Urination.

Abstract

Indole alkaloids including sedative activity of pyrazolone iodine methylate and pyrazolone chloride were caused by alcohol sleep and feeling against arousal or fear effects were studied by the Sonberg method. In this study, pyrazoline iodine methylate and pyrazaline chloride reduced sleep time by increasing the sleep time caused by alcohol, in the Sonberg method, the excretion of urine and excrement by experimental animals decreased due to noise and external factors. This indicates that the studied substances have a calming effect.

Published

2022-11-24

How to Cite

Yu. R. Mirzaev, T. T. Khamroev, E. M. Ruzimov, B. N. Khandamov, & Sh. M. Adizov. (2022). Evaluation of the Effect on the Nervous System of Substances with an Alkaloid Structure Having Antitumor Activity. Journal Healthcare Treatment Development, 2(06), 6–10. https://doi.org/10.55529/jhtd.26.6.10