Quality of Life of Kidney Transplant Donor at Shahid Dharmabhakta National Transplant Centre, Nepal

Abstract

Introduction: End-stage renal disease has a high rate of mortality and morbidity globally. Kidney transplantation remains the best treatment option in comparison to other forms of renal replacement. This study was carried out to compare QOL before and after donor nephrectomy. The aim of study was to assess the quality of life of the living donor Methods: A prospective cross-sectional study was conducted among 80 renal transplant donors of Shahid Dharmbhakta National Transplant Centre from February 2021 to February 2022. A consecutive sampling technique was done for data collection. Short Form 36 version 2 (SF36v2) was used to assess the quality of life of kidney donors. The interview was conducted by researcher just before and twelve months after the donor nephrectomy who came for follow up in that center. Score of eight domains of quality of life before and after transplant were compared with paired t-tests through SPSS software 20. Results: Out of eight domains of quality of life, physical functioning, fatigue, emotional well-being, pain and general health were decreased 12 months after donation. Domains of QOL; physical functioning, limitation due to physical health, Role limitation due to emotional problems, Energy Role, fatigue , Emotional wellbeing , social functioning, pain and general health, were compared using paired T-test. The result showed (M= 70.60 SD=18.67) before transplant and M= 66.92 SD= 17.30 one year post transplant. Mean decrease is M= 3.68, SD= 3.56, df= 7, (95% Cl 0.7, 6.6), p=0.02. Domain of Quality of life like Physical functioning (p=0.001), limitation due to physical health (p=0.01), energy role fatigue (p=0.001), pain and general health (p=0.001) were significantly associated with kidney donation in donors. Conclusion: The quality of life of renal transplant donors was affected by donor nephrectomy.