The Effect of the Thyroid Gland on High Blood Pressure

Abstract

The paper discusses the relationship between the thyroid gland and high blood pressure, specifically in the context of hyperthyroidism. It explains that hyperthyroidism, characterized by an increase in thyroid hormones, can lead to an acceleration of the heartbeat and an increase in its force, resulting in high blood pressure . The paper also mentions that high blood pressure resulting from other diseases, such as thyroid problems, is known as secondary hypertension. Treating this type of high blood pressure requires addressing the underlying medical condition causing it Additionally, the paper highlights that thyroid hormones play a role in regulating hemostasis, the process of blood clotting. Thyroxine, a thyroid hormone, is associated with the release of von Will brand factor and influences the synthesis of proteins involved in hemostasis. Thyroxine deficiency in hypothyroidism can lead to a deficiency in certain clotting factors Low serum levels of T3 can increase peripheral vascular resistance by up to 30%, leading to arterial stiffness and a decrease in cardiac output. This results in high blood pressure, particularly in systolic blood pressure, which returns to normal with treatment of the underlying thyroid dysfunction. Hypothyroidism is associated with high blood pressure, and the most common cardiovascular findings in hypothyroidism are bradycardia and high blood pressure. Thyroid hormone deficiency affects the contractility of cardiomyocytes, leading to an increase in peripheral vascular resistance and diastolic dysfunction. The presence of an antigen in patients with subclinical hypothyroidism may contribute to a potential hypercoagulable state, which can further impact blood pressure regulation.