Lipoproteins Levels in Rheumatoid Arthritis

Abstract

Introduction: Many studies found that people with rheumatoid arthritis (RA) had higher cardiovascular morbidity and death rates. Accelerated atherosclerosis is the primary cause of cardiovascular mortality. Strong risk factors for atherosclerotic events include increased plasma total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and reduced high-density lipoprotein cholesterol (HDL-C). The purpose of this study: This is to demonstrate how the serum lipid profile changes in RA patients. Methods: The lipid profile of 50 RA patients who satisfied the 2010 American College of Rheumatology (ACR) criteria for rheumatoid arthritis (RA) was assessed. Fifty volunteers who appeared to be in good health were used as the control group in this investigation. Both the patient and control groups' lipid profiles (TC, LDL-C, HDL-C, TG, VLDL, and atherogenic index) were calculated. Results: According to the study's findings, RA patients had a substantial increase in total cholesterol (P0.05), a significant decrease in LDL cholesterol (P0.05), and a significant increase in HDL cholesterol (P0.05). As a result, rheumatoid arthritis patients' atherogenic index ratio of TC/HDL-C (P0.0001) was considerably greater compared to control groups. Conclusion: Compared to the healthy control individual, the lipid profile of RA patients is atherogenic.